224 api engineer jobs at 100 companies in La Mesa, CA

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Graph/API Agentic Engineer
San Diego, California, United States
OnsiteFull Time
TargetCW
TargetCW: Private U.S. contingent-workforce management providing employers payrolling, staffing, employer-of-record, compliance, and workforce technology services.
Hands-on platform operations role owning APIs, integrations, and inline tools; requires expertise in API lifecycle, reliability, security, documentation, and business value.
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API Manufacturing Manager
San Diego, California, United States
$120k-$164k/yr OnsiteFull Time
Neurocrine Biosciences
Neurocrine BiosciencesNasdaq Global Select Market: NBIX: Develops treatments for neurological, psychiatric, endocrine, and immunological disorders.
6+ YOEBS/BA in Engineering, Science or related field with 6+ years CMC manufacturing/process development experience, or Master's with 4+ years; expertise in API CMC, cGMP, risk management, and process improvement tools.
3w
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System Test Engineer
Foster City or San Diego
$153k-$209k/yr HybridFull Time
Zoox
Zoox: Autonomous mobility developing a fully electric robotaxi fleet.
3+ YOEBachelor's or Master's in Computer Science, Aerospace Engineering, Electrical Engineering, or STEM; 3+ years testing complex systems; experience with Python, Pytest, REST API, Git; integrated systems troubleshooting.
Python, Pytest, REST API, Git, Jira, Azure DevOps, Linux, Unix
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Materials Engineer
San Diego, California, United States
$121k-$181k/yr OnsiteFull Time
Solar Turbines
Solar Turbines: Innovative, Sustainable Energy Solutions.
8+ YOEBachelor's degree in materials science, metallurgical engineering, or related field; 8+ years of industrial experience; expertise in ferrous metallurgy, material testing, failure analysis, heat treatment, and manufacturing processes.
ASME, AMS, ASTM, ISO, API, NACE
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Applied AI Engineer
San Francisco or Los Angeles or Washington or San Diego or Seattle or London
$150k-$170k/yr HybridFull Time
CHAOS Industries
CHAOS Industries: Redefining modern defense with a multi-product portfolio.
2+ YOERequires BS, MS, PhD, or equivalent experience in a technical field; 2–5 years software development experience; strong Python; production AI/ML systems, model evaluation, APIs, distributed systems, containers, CI/CD, and edge deployment.
Python, APIs, Containers, CI/CD, GPU
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Senior Staff Systems Engineer
San Diego, California, United States
$149k-$248k/yr OnsiteFull Time
Dexcom
DexcomNASDAQ: DXCM: Global leader in continuous glucose monitoring and diabetes management.
13+ YOEExpert systems engineering for large-scale connected software-enabled products; strong architecture, requirements, risk management, and cross-functional leadership experience; deep knowledge of mobile, cloud, APIs, and regulated medical systems.
Jama Connect, Jira, TestRail, GitHub, Ketryx, Cameo, Sparx EA, SysML, AWS, Azure, GCP, Bluetooth Low Energy (BLE)
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GPU Research Engineer
San Diego, California, United States
$134k-$200k/yr OnsiteFull Time
Qualcomm Technologies, Inc.
Qualcomm Technologies, Inc.: Developing semiconductor, wireless, connectivity, automotive, AI, and computing technologies for device and enterprise customers.
2+ YOERequires a relevant bachelor's degree with 2–6+ years, master's with 1–5+ years, or PhD with 0–4+ years of related engineering experience; GPU architecture, C/C++, and graphics API expertise required.
Vulkan, D3D, OpenGL, OpenCL, C, C++, Python, GPU, Adreno GPU, System on a Chip (SOC), GPU drivers
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Staff Engineer, Data Platform (R5659)
San Diego, California, United States
$150k-$230k/yr OnsiteFull Time
Shield AI
Shield AI: Developer of AI-powered autonomous systems for defense and aerospace.
Significant distributed data systems experience; strong Go or Python software engineering; expertise in data modeling, APIs, storage, Kubernetes, Linux, networking, security, observability, and infrastructure as code.
Go, Python, Kubernetes, Linux, Terraform, Helm, GitOps, Ray, Kafka, NATS, Redpanda, Apache Arrow, Parquet, OpenAPI, AsyncAPI, WebSockets, S3
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Services Engineer
Boston or Encinitas
$100k-$130k/yr HybridFull Time
Paperless Parts
Paperless Parts: Private manufacturing-software helping job shops and contract manufacturers quote faster.
US Citizenship or Green Card required due to export control laws. Strong Python, REST APIs, SQL, and integration architecture expertise; proven customer-facing execution and project management in SaaS.
Python, REST APIs, SQL, Docker, Jenkins, AWS, EC2, ECR, S3, IAM
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Forward Deployed Engineer - FDE - Remote
San Diego, California, United States
$177k-$303k/yr RemoteFull Time
Optum Insight
Optum Insight: Insight is a healthcare analytics and technology-services business serving payers, providers, governments and life sciences companies.
8+ YOE8+ years software engineering experience, 7+ years consulting experience, bachelor\u0002s in CS/Engineering/Data Science, experience deploying AI/ML and cloud solutions, proficiency with LLMs and stakeholder communication.
LLMs, APIs, Azure, AWS, GCP, CodeX, Claude
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Collaboration Technology and Workflow Engineer
San Francisco or New York or Santa Monica or Los Angeles or Palo Alto or Chicago or Washington, D.C. or Boston or Colorado or Seattle or San Diego or Reston
$115k-$160k/yr HybridFull Time
Cooley
Cooley: Private law firm advising technology, life sciences and high-growth companies on deals, litigation, intellectual property and regulation.
4+ YOERequires 4+ years of applicable experience, SharePoint Online and Power Platform expertise, modern web development with SPFx, React, and TypeScript, REST APIs, and automation experience. Bachelor's degree and Microsoft 365 certifications preferred.
Microsoft Exchange Online, Microsoft SharePoint Online, Microsoft Power Platform, Microsoft Power Automate, Microsoft Power Apps, Microsoft Dataverse, Microsoft 365, Microsoft Power BI, SPFx, React, TypeScript, Git, CI/CD, REST API, JSON, XML, Azure Services, Logic Apps, Azure Functions, Azure API Management, Python, JavaScript, CSS, KQL, Microsoft Graph API, iManage, Microsoft Office
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Staff Production Operations Engineer
San Diego, California, United States
$199k-$299k/yr HybridFull Time
Sony Interactive Entertainment
Sony Interactive Entertainment: Global leader in interactive entertainment, hardware, and digital network services.
10+ YOEBachelor's degree or equivalent and 10+ years supporting production services at scale, including 5+ years with AWS, Java/API services, incident management, cloud, Kubernetes, automation, observability, and architecture.
AWS, ALB, Route 53, API Gateway, Lambda, RDS, DynamoDB, ElastiCache, Docker, Kubernetes, EKS, UKS, Fargate, Python, Go, Java, GitHub, Git, Ansible, Chef, Terraform, CloudFormation, Jenkins, Spinnaker, Datadog, CloudWatch, Splunk, Grafana, BigPanda, Slack, JIRA, ServiceNow, SQL, MySQL, Oracle, Snowflake, Codex, Claude, Cursor
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Manufacturing Test Engineer
San Diego, California, United States
$85k-$110k/yr OnsiteFull Time
TrellisWare Technologies
TrellisWare Technologies: Private U.S. defense-communications developing tactical radios and resilient waveforms for military and public-safety users.
1+ YOEBachelor’s degree in a technical field, 1–8 years’ experience, automated test and manufacturing process development, programming, Linux and Windows systems, and hardware/software troubleshooting. U.S. citizenship required.
Python, C#, VB.NET, C/C++, Linux, Windows, spectrum analyzers, oscilloscopes, signal generators, radio emulators, network analyzers, RF switch matrices, multimeters, APIs, databases, PC
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Senior Autonomous Behavior Engineer
San Diego, California, United States
$120k-$200k/yr OnsiteFull Time
Apium Swarm Robotics
Apium Swarm Robotics: Private defense-technology developer building distributed autonomy and swarming software for drones, robotic platforms, and uncrewed surface vessels.
7+ YOERequires 7+ years in robotics, autonomy, modeling and simulation, or related fields; strong C++ and mathematics skills; autonomous behavior development; simulation experience; US citizenship; and cross-functional communication skills.
C++, Gazebo, ROS, AirSim, SITL, Team Awareness Kit (TAK), Cursor on Target (CoT), MAVLink, PX4, ArduPilot, Unity, Unreal, CI/CD, API
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Automation and Systems engineer
San Diego, California, United States
OnsiteFull Time
Zucarmex
Zucarmex: Private Mexican sugar producer and distributor that grows, mills, refines, and markets sugar for manufacturers and retailers.
1+ YOEBachelor's degree in a related technical field preferred, 1+ year of hands-on application development, industrial programming, PLC, or plant software experience, plus proficiency with PLC, HMI, web, and automation systems.
Google Apps Script, JavaScript, HTML, CSS, Python, Google Workspace, iPad, APIs, Allen-Bradley, Studio 5000, RSLogix, Siemens, TIA Portal, FactoryTalk View, WinCC, HMI, SCADA, PID, 4-20 mA, HART, RTDs, EtherNet/IP, Profinet, Modbus TCP/RTU, VFDs, Allen-Bradley PowerFlex, Siemens Sinamics, P&IDs, IEC 61131-3, Ladder, Structured Text
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Senior Networking Professional Services Engineer - Top Secret/SCI w/CI Poly Clearance Required
California or Virginia or Maryland or District of Columbia or San Diego
$136k-$275k/yr RemoteFull Time
Hewlett Packard Enterprise
Hewlett Packard EnterpriseNYSE: HPE: Global edge-to-cloud advancing how people live and work.
7+ YOEUS citizenship; active TS/SCI with CI Poly clearance; 7+ years hands-on network engineering; deep routing/switching knowledge (EVPN, OSPF, BGP, MPLS); Juniper MX and Routing Director support; 25% travel; remote role.
Juniper MX, Routing Director, EVPN, Multicast, OSPF, BGP, RSVP, LDP, Pseudo wires, L2VPN, L3VPN, MPLS Traffic Engineering, GRE, VXLAN, XML API, NETCONF, REST API, gRPC, Python, PyEZ, ncclient, Ansible, Jinja2, SLAX
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UiPath Solutions Architect / Senior RPA Developer
San Diego, California, United States
$130k/yr OnsiteFull Time
Ignite Digital Services
Ignite Digital Services: Private U.S. government-services contractor providing analytics, data science, and program support to national security agencies.
5+ YOERequires 5+ years of technical experience, 3+ years of UiPath experience including Apps, API integration expertise, bachelor's degree or equivalent, and ability to obtain and maintain a DoD security clearance.
UiPath, UiPath Apps, UiPath Orchestrator, REST APIs, OData, JSON, OAuth 2.0, Microsoft Power Platform, Microsoft Power Apps, Microsoft Power BI, Microsoft SharePoint, Microsoft Teams, Jira, SAP, SQL, JavaScript, TypeScript, React, HTML, CSS, Git
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Software Engineer
San Diego, California, United States
$130k-$160k/yr HybridFull Time
GALT Aerospace
GALT Aerospace: Private U.S. defense contractor designing and integrating airborne communications, networking, and mission systems for government and military customers.
5+ YOEBachelor's degree in computer science, software engineering, computer engineering, or related STEM field; 5+ years' software development experience; proficiency with Python, JavaScript, Linux, Git, Ansible, containers, APIs, and distributed systems; U.S. citizenship and ability to obtain a DoD clearance.
Python, JavaScript, Vue.js, RESTful APIs, Bash, PowerShell, Red Hat Enterprise Linux (RHEL), RPC, Protocol Buffers (Protobuf), gRPC, Ansible, Podman, Git, Windows, Linux, Ollama, Open WebUI, vLLM, Hugging Face, Model Context Protocol (MCP), Jenkins, GitLab CI/CD, TCP/IP, UDP, DNS, GPIO, Redis, PostgreSQL
2mo
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Cybersecurity Engineer II
San Diego, California, United States
$110k-$130k/yr OnsiteFull Time
Lyntris
LyntrisNYSE: LYNX: Defense technology providing sensing hardware, AI-driven data fusion, and mission systems to U.S. and allied warfighters.
5+ YOERequires 5–7+ years of cybersecurity or network defense experience, a technical bachelor's degree, active or obtainable U.S. national security clearance, and enterprise cybersecurity, Splunk, IDS/IPS, firewall, Tenable, Wireshark, API, scripting, and automation experience.
Splunk Enterprise, Splunk Enterprise Security, SIEM, IDS/IPS, Wireshark, Tenable, Tenable Nessus, Tenable.sc, Palo Alto, Cisco Firepower, Trellix NX, Python, PowerShell, Bash, REST APIs, APIs, Windows, Linux/Unix, network taps, firewalls
2w
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Senior Manager, Research Intelligence Engineer
Princeton or Tampa or San Diego or Cambridge or Brisbane
$135k-$180k/yr OnsiteFull Time
Bristol Myers Squibb
Bristol Myers SquibbNYSE: BMY: Transforming patients' lives through science.
6+ YOEBachelor's degree in computer science, engineering, data science, or life sciences; 6+ years experience in production data/software/analytics; hands-on generative AI/agentic systems; Python, SQL, APIs, cloud data platforms, CI/CD; strong communication and mentoring skills.
Databricks, Python, SQL, APIs, CI/CD